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    kdpay钱包(中国) /药靶模型 /GPCR靶点细胞 /Class A(Rhodopsin) /EDNRB/CHO

    EDNRB/CHO

    CBP71101

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    I. Background
    EDNRB (Endothelin Receptor Type B) is a Protein Coding gene. Diseases associated with EDNRB include Waardenburg Syndrome, Type 4A and Abcd Syndrome. Among its related pathways are Class A/1 (Rhodopsin-like receptors) and Endothelins. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and type 1 angiotensin receptor binding. 
     
    II. Introduction
    Host Cell:

    CHO

    Stability: 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
    Freeze Medium: 90% FBS+10% DMSO
    Culture Medium: F12K+10%FBS+5ug/ml puromycin
    Mycoplasma Status: Negative
    Storage: Liquid nitrogen immediately upon delivery
    Application(s):

    Functional assay for EDNRB

    Transducer: Gq
     
    Ⅲ. Description of Host Cell Line
    Organism: Hamster
    Tissue: Ovary
    Morphology: Epithelial
    Growth Properties: Adherent
     
    Ⅳ. Representative Data

    Figure 1. Endothelin 1 efffect on CHO-EDNRB clone 6.


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