KK-LC-1/MC-38
CBPG0056
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产品描述
产品数据库
| I. Background | |
| KK-LC-1一种极具前景的癌症免疫治疗新靶点。 它是一种在正常情况下仅于睾丸中表达的癌-睾丸抗原，而在肺癌、胃癌、肝癌等多种实体瘤中均有特异性高表达，这一特性使其成为了开发精准免疫疗法的理想“路标”。 | |
| II. Introduction | |
| Host Cell: | MC-38 |
| Expressed gene: | KK-LC-1 |
| Stability: | 32 passages |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+10%FBS+2μg/ml Puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| III. Description of Host Cell Line | |
| Organism: | Mouse |
| Tissue: | Colon |
| Morphology: | Epitheloid cell |
| Growth Properties: | Adherent |
| IV. Representative Data | |
 Figure 1. Recombinant KK-LC-1/MC-38 constitutively expressing KK-LC-1. |
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| V. In VIVO Data | |
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Index |
Content |
|
Animal |
C57BL/6J, 7weeks, female |
|
Implanted Position |
Subcutaneous (right flank region) |
|
Injected Cell Numbers |
1×10^6/0.1ml |
|
Matrix gel |
Without matrix gel |
1. Weight Change
Figure 2. KK-LC-1/MC38 Mean Body Weight ± SEM.
2. Tumor Volume
Figure 3. KK-LC-1/MC38 Mean Tumor Volume ± SEM.
NOTE：The above data was provided by Cobioer (cell data) and Truway Bio (in vivo data model).
